Product Name:5-Cyclopropyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carbonyl chloride

IUPAC Name:5-cyclopropyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carbonyl chloride

CAS:861452-41-7
Molecular Formula:C11H7ClF3N3O
Purity:95%+
Catalog Number:CM271892
Molecular Weight:289.64

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CM271892-1g 1-2 Weeks ƏijƏ
CM271892-5g 1-2 Weeks ǎǟǎ

For R&D use only.

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Product Details

CAS NO:861452-41-7
Molecular Formula:C11H7ClF3N3O
Melting Point:-
Smiles Code:O=C(Cl)C1=C2N=C(C3CC3)C=C(C(F)(F)F)N2N=C1
Density:
Catalog Number:CM271892
Molecular Weight:289.64
Boiling Point:
MDL No:MFCD03422916
Storage:

Category Infos

Pyrazolopyrimidines
Pyrazolopyrimidine scaffolds are one of the most important heterocyclic compounds in drug discovery. This scaffold has various biological activities, among which anticancer is an important one.
Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.

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