Product Name:3-(4-amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione hemihydrate

IUPAC Name:bis(3-(4-amino-1-oxo-2,3-dihydro-1H-isoindol-2-yl)piperidine-2,6-dione) hydrate

CAS:847871-99-2
Molecular Formula:C26H28N6O7
Purity:95%+
Catalog Number:CM133051
Molecular Weight:536.55

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CM133051-1g 3-4 Weeks ƥǑƛ

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Product Details

CAS NO:847871-99-2
Molecular Formula:C26H28N6O7
Melting Point:-
Smiles Code:O=C(C(N(CC1=C2C=CC=C1N)C2=O)CC3)NC3=O.[H]O[H].O=C(C(N(CC4=C5C=CC=C4N)C5=O)CC6)NC6=O
Density:
Catalog Number:CM133051
Molecular Weight:536.55
Boiling Point:
MDL No:
Storage:

Category Infos

PROTAC-E3 Ligase Ligands
Bifunctional degrader molecules, also called proteolysis-targeting chimeras (PROTACs), are a new modality of chemical tools and potential therapeutics to understand and treat human disease. A required PROTAC component is a ligand binding to an E3 ubiquitin ligase, which is then joined to another ligand binding to a protein to be degraded via the ubiquitin–proteasome system. The advent of nonpeptidic small-molecule E3 ligase ligands revolutionized the field and ushered in the design of drug-like PROTACs with potent and selective degradation activity.
PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
Proteolysis-Targeting Chimeras | PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
PROTAC (Proteolysis-Targeting Chimeras) is a promising approach in drug discovery that involves the use of small molecules to target specific proteins for degradation by the cellular machinery.


Product Other Information

Product Overview 3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione hemihydrate is a remarkable chemical compound that encapsulates the essence of innovation and scientific exploration. This complex molecule, often referred to by its systematic name, has garnered significant attention in the world of chemistry, pharmaceuticals, and research due to its unique and multifaceted structure. Our company proudly presents this compound as a versatile chemical building block with a broad range of applications and the potential to drive innovation across various industries.
Molecular Structure At its core, 3-(4-amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione hemihydrate showcases a captivating arrangement of atoms and functional groups. Breaking down its name elucidates its structural components:

3-(4-amino-1-oxoisoindolin-2-yl): This segment consists of an isoindoline ring with a keto group and an amino group at precise positions. Isoindoline is a bicyclic structure, known for its stability and presence in various natural products and pharmaceuticals. The addition of an amino and keto group at specific sites introduces reactivity and the potential for diverse chemical interactions.

piperidine: Incorporating a piperidine ring into the molecule contributes to its cyclic nature. Piperidine is a six-membered nitrogen-containing heterocycle, and its inclusion often imparts biological activity to molecules.

2,6-dione: This portion signifies the presence of two carbonyl (dione) groups on the molecule, which can participate in various chemical reactions, including nucleophilic additions and redox processes.

Hemihydrate: The term "hemihydrate" indicates that the compound contains water molecules integrated into its crystal lattice, which can have implications for its physical properties and stability.
Key Features and Benefits Structural Complexity: The compound's intricate structure combines an isoindoline ring, a piperidine ring, and dione functional groups. This complexity offers diverse opportunities for chemical modification and reactivity, making it a valuable asset for synthetic chemists.

Pharmacological Potential: Compounds featuring isoindoline and piperidine moieties have shown promise in pharmaceutical research. This compound can serve as a starting point for the development of novel drugs targeting a wide range of therapeutic areas, including neurology and oncology.

Crystallography and Material Science: The presence of hemihydrate in the compound's structure opens doors for crystallographic studies. Researchers can explore its crystalline properties, which can be crucial for materials science applications.

Synthetic Methodology: The synthesis of 3-(4-amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione hemihydrate involves complex chemical reactions, making it an excellent model compound for the development and refinement of synthetic methodologies.
Quality Assurance Our product undergoes rigorous quality control measures to ensure its purity, consistency, and compliance with industry standards. We guarantee that 3-(4-amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione hemihydrate supplied by Chemenu will meet your exacting specifications.
Availability We offer this compound in various quantities, from small research-scale quantities to bulk production quantities, catering to the diverse needs of our customers. Our efficient supply chain ensures timely delivery to meet your project timelines.