Product Name:methyl cis-4-hydroxycyclohexanecarboxylate

IUPAC Name:methyl (1s,4s)-4-hydroxycyclohexane-1-carboxylate

CAS:3618-03-9
Molecular Formula:C8H14O3
Purity:97%
Catalog Number:CM104761
Molecular Weight:158.2

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CM104761-25g in stock ƛȯ

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Product Details

CAS NO:3618-03-9
Molecular Formula:C8H14O3
Melting Point:-
Smiles Code:COC(=O)[C@@H]1CC[C@H](O)CC1
Density:
Catalog Number:CM104761
Molecular Weight:158.2
Boiling Point:
MDL No:MFCD20441962
Storage:

Category Infos

Cyclohexanes
Cyclohexane is an organic compound with a chemical formula C6H12. It is a colorless liquid with a pungent odor, insoluble in water, and soluble in most organic solvents such as ethanol, ether, benzene, and acetone. Cyclohexyl fragments are a common structure in both natural and synthetic drugs. It can be used as both core structure and part of achiral side chain.

Column Infos

Cyclanes
Cyclanes are secondary metabolites that can be found in plants, and are also biochemicals that can be used in medicine. Cyclanes are found in pine trees, and are used in the making of plastics. Cyclenes are found in cinnamon, and have antifungal properties.
KT-474
Kymera announced that the first patient has been dosed in the randomized Phase 2 clinical trial in hidradenitis suppurativa (HS) evaluating KT-474 (SAR444656). The Phase 2 study will evaluate the efficacy, safety, pharmacokinetics, and biological effects of KT-474 compared with placebo in adult patients with moderate to severe HS. Kymera's partner Sanofi is conducting the Phase 2 study in HS, and has initiated a second randomized Phase 2 trial in AD. Under the terms of the collaboration, dosing of the first patient in the HS trial generated a milestone payment of $40 million. KT-474 is an oral IRAK4 degrader, in development for the treatment of IL-1R/TLR-driven complex inflammatory diseases where there is an opportunity to significantly advance the standard of care, including HS and AD. Sanofi, which is collaborating with Kymera on the development of KT-474 outside of the oncology and immune-oncology fields, is conducting the Phase 2 studies.
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