Piperidine is an azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. Although piperidine is a common organic compound, it is an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.
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Iptacopan is the first oral targeted inhibitor of complement system regulator factor B, which blocks the alternative pathway amplification cycle by inhibiting factor B, and is used to treat complement-driven renal disease (CARD).
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