A spiro compound is a polycyclic compound in which two monocyclic rings share one carbon atom; the shared carbon atom is called a spiro atom. Spiro compounds have rigid structures, stable structures, and have special properties that general organic compounds do not possess, such as anomeric effect, spiro conjugation and spiro hyperconjugation. Compared with the monocyclic structure or the planar aromatic structure, the spiro structure has a larger three-dimensional structure; the heterocyclic spiro structure is also regarded as the biological isostere of some groups, which can change the drug to a certain extent. The water solubility, lipophilicity, dominant conformation and ADMET properties of the molecule make the optimized lead molecule easier to drug. Therefore, spiro compounds occupy a very important position in drug development.
Spiro And Bicyclic Compound
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The most common type of organic photodetector is the organic photodiode (OPD). The photodiode has a simple structure in which an active layer is sandwiched between a transparent electrode and a metal electrode. In contrast to OLEDs, organic photodiodes (OPDs) utilize the organic semiconductor to absorb incident light and convert it to electric current. The structure and working principle are more like organic solar cells. Among the various organic photodetectors, organic photodiodes (OPDs) have been the most widely studied due to their fast response, high sensitivity, and full use of the existing research base of organic photovoltaics (OPVs).