Product Name:3,3-Di-(phthalimidomethyl)oxetane

IUPAC Name:2-({3-[(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)methyl]oxetan-3-yl}methyl)-2,3-dihydro-1H-isoindole-1,3-dione

CAS:198572-34-8
Molecular Formula:C21H16N2O5
Purity:95%+
Catalog Number:CM741865
Molecular Weight:376.37

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CM741865-100mg in stock ȯǫƥ
CM741865-250mg in stock ƃŞǫ
CM741865-1g in stock ŞǫȯȐ

For R&D use only.

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Product Details

CAS NO:198572-34-8
Molecular Formula:C21H16N2O5
Melting Point:-
Smiles Code:O=C1N(CC2(CN3C(=O)C4=CC=CC=C4C3=O)COC2)C(=O)C2=CC=CC=C12
Density:
Catalog Number:CM741865
Molecular Weight:376.37
Boiling Point:
MDL No:MFCD14585336
Storage:

Category Infos

Oxetanes
Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.