Product Name:2-[(2-ethyl-8-methyl-6-piperazin-1-ylimidazo[1,2-a]pyridin-3-yl)-methylamino]-4-(4-fluorophenyl)-1,3-thiazole-5-carbonitrile

IUPAC Name:2-{[2-ethyl-8-methyl-6-(piperazin-1-yl)imidazo[1,2-a]pyridin-3-yl](methyl)amino}-4-(4-fluorophenyl)-1,3-thiazole-5-carbonitrile

CAS:1628260-77-4
Molecular Formula:C25H26FN7S
Purity:95%+
Catalog Number:CM1015346
Molecular Weight:475.59

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Product Details

CAS NO:1628260-77-4
Molecular Formula:C25H26FN7S
Melting Point:-
Smiles Code:CCC1=C(N2C=C(C=C(C2=N1)C)N3CCNCC3)N(C)C4=NC(=C(S4)C#N)C5=CC=C(C=C5)F
Density:
Catalog Number:CM1015346
Molecular Weight:475.59
Boiling Point:
MDL No:
Storage:

Category Infos

Thiazoles
Thiazoles are very important functional groups in medicinal chemistry. They act as ligands on a variety of biological matrices. Thiazoles are used in a wide range of therapeutic applications, such as antibacterial, antiretroviral, antifungal, antiallergic, antihypertensive, pain treatment, and to control symptoms of schizophrenia.
Piperazines
Piperazine is an organic compound consisting of a six-membered ring containing two nitrogen atoms in opposite positions in the ring. The chemical formula of piperazine is C4H10N2, and it is an important pharmaceutical intermediate. Pyrimidines and piperazines are known to be the backbone of many bulk compounds and important core structures for approved drugs; studies have shown that combining a pyridine ring with a piperazine moiety within a single structural framework enhances biological activity.
Imidazopyridines
With four imidazopyridine-containing drugs and one pyrazolopyridine-containing drug on the market, bicyclic pyridines containing ring-junction nitrogen are privileged structures in medicinal chemistry. With two nitrogen atoms with potential to serve as hydrogen bond acceptors, imidazopyridines and pyrazolopyridines may boost binding to target proteins and elevate potency. In addition, these structures have found utility in FBDD, covalent inhibitors, reducing metabolic liabilities, and creating novel chemical space and intellectual properties. With many of the advanced intermediates now commercially available, they will find more and more applications in drug discovery.
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