Benzene is an important organic compound with the chemical formula C6H6, and its molecule consists of a ring of 6 carbon atoms, each with 1 hydrogen atom. Benzene is a sweet, flammable, colorless and transparent liquid with carcinogenic toxicity at room temperature, and has a strong aromatic odor. It is insoluble in water, easily soluble in organic solvents, and can also be used as an organic solvent itself. The ring system of benzene is called benzene ring, and the structure after removing one hydrogen atom from the benzene ring is called phenyl. Benzene is one of the most important basic organic chemical raw materials. Many important chemical intermediates can be derived from benzene through substitution reaction, addition reaction and benzene ring cleavage reaction.
Evaluate Pharma recently issued an article listing "the most valuable potential drugs currently under development", and Aficamten is one of them. Aficamten is a novel cardiac myosin inhibitor for the treatment of hypertrophic cardiomyopathy, which achieves its therapeutic effect by reducing the hypercontractility of obstructive HCM and improving diastolic function.