Product Name:4-bromo-2-chloro-1-cyclopropyl-1H-benzo[d]imidazole

IUPAC Name:4-bromo-2-chloro-1-cyclopropyl-1H-1,3-benzodiazole

CAS:1416713-06-8
Molecular Formula:C10H8BrClN2
Purity:95%
Catalog Number:CM110746
Molecular Weight:271.54

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CM110746-100mg in stock ȃŗů
CM110746-250mg in stock ŗIJů
CM110746-1g in stock IJIJȃƥ

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Product Details

CAS NO:1416713-06-8
Molecular Formula:C10H8BrClN2
Melting Point:-
Smiles Code:ClC1=NC2=C(Br)C=CC=C2N1C3CC3
Density:
Catalog Number:CM110746
Molecular Weight:271.54
Boiling Point:
MDL No:
Storage:

Category Infos

Benzimidazoles
Benzimidazole is a benzo derivative of imidazole. It is a kind of bicyclic aromatic organic compounds, which is formed by fusing a six-membered benzene ring and five-membered imidazole at positions 4 and 5 of imidazole ring. It is an important pharmacophore of many biologically active heterocyclic compounds with various pharmacological activities. Benzimidazoles and their derivatives have developed into dynamic heterocyclic systems due to their potency in a variety of biologically active compounds such as anticancer, bactericidal and antiviral drugs. Benzimidazoles are a class of therapeutic motifs with broad relevance in medicinal chemistry.
Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.

Column Infos

Benzo Heterocycles
Benzoheterocycles are heterocycles which are fused with a benzene ring. Coumarone, thianaphthene, benzopyridine, isoquinoline, and dibenzopyridine all belong to this class of compounds.

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