Product Name:tert-butyl 7-hydroxy-2-azaspiro[3.5]nonane-2-carboxylate

IUPAC Name:tert-butyl 7-hydroxy-2-azaspiro[3.5]nonane-2-carboxylate

CAS:1363383-18-9
Molecular Formula:C13H23NO3
Purity:97%
Catalog Number:CM106701
Molecular Weight:241.33

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Product Details

CAS NO:1363383-18-9
Molecular Formula:C13H23NO3
Melting Point:-
Smiles Code:O=C(N1CC2(CCC(O)CC2)C1)OC(C)(C)C
Density:
Catalog Number:CM106701
Molecular Weight:241.33
Boiling Point:
MDL No:MFCD20926146
Storage:

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Spiro Compounds
A spiro compound is a polycyclic compound in which two monocyclic rings share one carbon atom; the shared carbon atom is called a spiro atom. Spiro compounds have rigid structures, stable structures, and have special properties that general organic compounds do not possess, such as anomeric effect, spiro conjugation and spiro hyperconjugation. Compared with the monocyclic structure or the planar aromatic structure, the spiro structure has a larger three-dimensional structure; the heterocyclic spiro structure is also regarded as the biological isostere of some groups, which can change the drug to a certain extent. The water solubility, lipophilicity, dominant conformation and ADMET properties of the molecule make the optimized lead molecule easier to drug. Therefore, spiro compounds occupy a very important position in drug development.
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Azetidines
Azetidines are an important class of saturated four-membered nitrogen-containing heterocyclic compounds. The research hotspots related to this structure mainly focus on two aspects: one is the research of pharmaceutical chemistry; the other is related to chiral azetidines, using rigid azetidine compounds as chiral ligands for asymmetric catalytic reactions. Many nitrogen-containing heterocycles play important roles in drug structures, and in many cases small structural changes can improve ligand selectivity and pharmacokinetic properties.
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Cyclohexanes
Cyclohexane is an organic compound with a chemical formula C6H12. It is a colorless liquid with a pungent odor, insoluble in water, and soluble in most organic solvents such as ethanol, ether, benzene, and acetone. Cyclohexyl fragments are a common structure in both natural and synthetic drugs. It can be used as both core structure and part of achiral side chain.

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