Product Name:propan-2-yl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene-1-sulfonate

IUPAC Name:propan-2-yl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene-1-sulfonate

CAS:1324003-62-4
Molecular Formula:C15H23BO5S
Purity:95%+
Catalog Number:CM1045561
Molecular Weight:326.21

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Product Details

CAS NO:1324003-62-4
Molecular Formula:C15H23BO5S
Melting Point:-
Smiles Code:CC(C)OS(=O)(=O)C1=C(C=CC=C1)B1OC(C)(C)C(C)(C)O1
Density:
Catalog Number:CM1045561
Molecular Weight:326.21
Boiling Point:
MDL No:
Storage:

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Boronic Acids and Esters
Boronic acids and boronate esters are commonly used reagents in Suzuki–Miyaura coupling chemistry. Organoboron derivatives are common reagents for C–C bond formation, either through classical palladium-mediated transformations or through other newer coupling methods. Boronic esters and acids are potential intermediates in the manufacture of many active pharmaceutical ingredients (API).
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Sparsentan
CSL Vifor and Travere Therapeutics announce European Commission approves FILSPARI(sparsentan) for the treatment of IgA Nephropathy (IgAN). First non-immunosuppressive therapy for the treatment of IgAN approved in Europe.
Sparsentan is a novel, non-immunosuppressive, single-molecule, dual endothelin angiotensin receptor antagonist with high selectivity for the endothelin A receptor (ETAR) and the angiotensin II subtype 1 receptor (AT1R). Pre-clinical data have shown that blockade of both endothelin type A and angiotensin II type 1 pathways in forms of rare chronic kidney disease, protects podocytes, prevents glomerulosclerosis and mesangial cell proliferation, and reduces proteinuria. 

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