Product Name:N-(4-{[(1H-indazol-6-yl)carbamoyl]methyl}-1,3-thiazol-2-yl)pyrimidine-2-carboxamide

IUPAC Name:N-(4-{[(1H-indazol-6-yl)carbamoyl]methyl}-1,3-thiazol-2-yl)pyrimidine-2-carboxamide

CAS:1286700-17-1
Molecular Formula:C17H13N7O2S
Purity:95%+
Catalog Number:CM960185
Molecular Weight:379.4

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Product Details

CAS NO:1286700-17-1
Molecular Formula:C17H13N7O2S
Melting Point:-
Smiles Code:O=C(CC1=CSC(NC(=O)C2=NC=CC=N2)=N1)NC1=CC=C2C=NNC2=C1
Density:
Catalog Number:CM960185
Molecular Weight:379.4
Boiling Point:
MDL No:
Storage:

Category Infos

Thiazoles
Thiazoles are very important functional groups in medicinal chemistry. They act as ligands on a variety of biological matrices. Thiazoles are used in a wide range of therapeutic applications, such as antibacterial, antiretroviral, antifungal, antiallergic, antihypertensive, pain treatment, and to control symptoms of schizophrenia.
Indazoles
Indazoles are a class of organic heterocyclic compounds, also known as 1,2-diazaindene and benzopyrazole. Indazole is a good bioisomer of phenol, which is more lipophilic than phenol and less prone to phase I and II metabolism. Indazole derivatives have a wide range of biological activities, and it has been confirmed that indazole compounds have anti-tumor, analgesic, anti-inflammatory and other drug activities. Anticancer is the most important application field of indazole drugs. Renal cell carcinoma, solid tumor, nausea and vomiting caused by chemotherapy and leukemia are the main indications of this structural backbone drug.
Pyrimidines
Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.