Product Name:(1R,2R)-1-((tert-Butoxycarbonyl)amino)-2-(difluoromethyl)cyclopropane-1-carboxylic acid

IUPAC Name:(1R,2R)-1-{[(tert-butoxy)carbonyl]amino}-2-(difluoromethyl)cyclopropane-1-carboxylic acid

CAS:1152134-45-6
Molecular Formula:C10H15F2NO4
Purity:95%+
Catalog Number:CM554539
Molecular Weight:251.23

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Product Details

CAS NO:1152134-45-6
Molecular Formula:C10H15F2NO4
Melting Point:-
Smiles Code:O=C([C@]1(NC(OC(C)(C)C)=O)[C@H](C(F)F)C1)O
Density:
Catalog Number:CM554539
Molecular Weight:251.23
Boiling Point:
MDL No:MFCD28664714
Storage:

Category Infos

Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.

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