Product Name:N-[6-[2-[(Cyclohexylmethyl)amino]-4- (trifluoromethyl)phenyl]-4-pyrimidinyl]-6- benzothiazolamine

IUPAC Name:N-(6-{2-[(cyclohexylmethyl)amino]-4-(trifluoromethyl)phenyl}pyrimidin-4-yl)-1,3-benzothiazol-6-amine

CAS:1026876-55-0
Molecular Formula:C25H24F3N5S
Purity:95%+
Catalog Number:CM360442
Molecular Weight:483.56

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Product Details

CAS NO:1026876-55-0
Molecular Formula:C25H24F3N5S
Melting Point:-
Smiles Code:FC(C1=CC=C(C2=CC(NC3=CC=C4N=CSC4=C3)=NC=N2)C(NCC5CCCCC5)=C1)(F)F
Density:
Catalog Number:CM360442
Molecular Weight:483.56
Boiling Point:
MDL No:
Storage:

Category Infos

Pyrimidines
Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.
Fluorinated Compounds
Fluorine is the most electronegative element in the periodic table, and the fluorine atom has a small atomic radius, so fluorine-containing organic compounds have many wonderful properties. For example, the introduction of fluorine atoms or fluorine-containing groups into drug molecules can improve the permeability to cell membranes, metabolic stability and bioavailability; in addition, the introduction of fluorine atoms will improve the lipid solubility of the compound and promote its absorption in the body. The speed of delivery changes the physiological effect. In the field of medicinal chemistry, the introduction of fluorine atoms into organic molecules is an important direction for the development of new anticancer drugs, antitumor drugs, antiviral agents, anti-inflammatory drugs, and central nervous system drugs.
Benzothiazoles
Benzothiazoles are aromatic heterocyclic compounds with the chemical formula C7H5NS. Benzothiazoles and their derivatives are a very important class of heterocyclic compounds that are ubiquitous in nature and are mainly used in medicine, agriculture and industry. In medicine, benzothiazole derivatives are a kind of very important pharmaceutical intermediates with good pharmacological and biological activities. It can be used as a fungicide, anti-tuberculosis drug, anti-malarial, anti-convulsant, insecticide, sedative and anti-inflammatory drug, and can also be used to treat diabetes and has anti-cancer effects.
Cyclohexanes
Cyclohexane is an organic compound with a chemical formula C6H12. It is a colorless liquid with a pungent odor, insoluble in water, and soluble in most organic solvents such as ethanol, ether, benzene, and acetone. Cyclohexyl fragments are a common structure in both natural and synthetic drugs. It can be used as both core structure and part of achiral side chain.