cas 1012104-68-5|| where to buy 1-(4-hydroxycyclohexyl)-N-isopentyl-2-((5-(2-(trifluoromethoxy)phenyl)-1H-indazol-3-yl)amino)-1H-benzo[d]imidazole-5-carboxamide

Product Name:1-(4-hydroxycyclohexyl)-N-isopentyl-2-((5-(2-(trifluoromethoxy)phenyl)-1H-indazol-3-yl)amino)-1H-benzo[d]imidazole-5-carboxamide

IUPAC Name:1-(4-hydroxycyclohexyl)-N-(3-methylbutyl)-2-({5-[2-(trifluoromethoxy)phenyl]-1H-indazol-3-yl}amino)-1H-1,3-benzodiazole-5-carboxamide

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: CAS NO:1012104-68-5; Molecular Formula:C33H35F3N6O3; Melting Point:-; Smiles Code:O=C(C1=CC=C2C(N=C(NC3=NNC4=C3C=C(C5=CC=CC=C5OC(F)(F)F)C=C4)N2C6CCC(O)CC6)=C1)NCCC(C)C; Density:

: Catalog Number:CM150383; Molecular Weight:620.68; Boiling Point:; MDL No:; Storage:

: Indazoles; Indazoles are a class of organic heterocyclic compounds, also known as 1,2-diazaindene and benzopyrazole. Indazole is a good bioisomer of phenol, which is more lipophilic than phenol and less prone to phase I and II metabolism. Indazole derivatives have a wide range of biological activities, and it has been confirmed that indazole compounds have anti-tumor, analgesic, anti-inflammatory and other drug activities. Anticancer is the most important application field of indazole drugs. Renal cell carcinoma, solid tumor, nausea and vomiting caused by chemotherapy and leukemia are the main indications of this structural backbone drug.

: Fluorinated Compounds; Fluorine is the most electronegative element in the periodic table, and the fluorine atom has a small atomic radius, so fluorine-containing organic compounds have many wonderful properties. For example, the introduction of fluorine atoms or fluorine-containing groups into drug molecules can improve the permeability to cell membranes, metabolic stability and bioavailability; in addition, the introduction of fluorine atoms will improve the lipid solubility of the compound and promote its absorption in the body. The speed of delivery changes the physiological effect. In the field of medicinal chemistry, the introduction of fluorine atoms into organic molecules is an important direction for the development of new anticancer drugs, antitumor drugs, antiviral agents, anti-inflammatory drugs, and central nervous system drugs.

: Benzimidazoles; Benzimidazole is a benzo derivative of imidazole. It is a kind of bicyclic aromatic organic compounds, which is formed by fusing a six-membered benzene ring and five-membered imidazole at positions 4 and 5 of imidazole ring. It is an important pharmacophore of many biologically active heterocyclic compounds with various pharmacological activities. Benzimidazoles and their derivatives have developed into dynamic heterocyclic systems due to their potency in a variety of biologically active compounds such as anticancer, bactericidal and antiviral drugs. Benzimidazoles are a class of therapeutic motifs with broad relevance in medicinal chemistry.

: Cyclohexanes; Cyclohexane is an organic compound with a chemical formula C6H12. It is a colorless liquid with a pungent odor, insoluble in water, and soluble in most organic solvents such as ethanol, ether, benzene, and acetone. Cyclohexyl fragments are a common structure in both natural and synthetic drugs. It can be used as both core structure and part of achiral side chain.