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Non-cleavable linkers

Noncleavable linkers consist of stable bonds that resist proteolytic degradation and provide higher stability than the cleavable linkers.

Cholesterol-TEG

Cholest-5-en-3-ol (3β)-, 3-(22-hydrogen 17-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-19-oxo-6,9,12,15,18-pentaoxa-2-azadocosanedioate)

3-[(2-Trifluoroacetamido)-ethoxy]-propyne

Methyl 2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethylamino]acetatehydrochloride

2-(6-(bis(4-methoxyphenyl)(phenyl)methoxy)-5-(hydroxymethyl)hexyl)isoindoline-1,3-dione

4-[3-[bis(4-methoxyphenyl)-phenylmethoxy]propoxy]-4-oxobutanoic acid,triethylamine salt

1,3-di-(4,4'-dimethoxyltrityl)-2-Succinate-Glycerol,triethylamine salt

(2S)-6-[[rel-(1R,8S,9s)-9-bicyclo[6.1.0]non-4-ynyl]methoxycarbonylamino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid

[rel-(1S,8R,9r)-9-bicyclo[6.1.0]non-4-ynyl]methyl N-[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]carbamate

4-[(2,5-dioxopyrrol-1-yl)methyl]cyclohexanecarboxamide

5-amino-1-(2-azatricyclo[10.4.0.0⁴⁹]hexadeca-1(12),4(9),5,7,13,15-hexaen-10-yn-2-yl)pentan-1-one

9-bicyclo[6.1.0]non-4-ynylmethyl N-[2-[2-[2-[(2-aminooxyacetyl)amino]ethoxy]ethoxy]ethyl]carbamate

(2R,6S,6aS)-6-triphenylsilyloxy-1,2,4,5,6,6a-hexahydropentalen-2-ol

Poly(oxy-1,2-ethanediyl),α-[2-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethyl]-ω-[3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy]-

9-bicyclo[6.1.0]non-4-ynylmethyl N-[4-(2-cyanoethynyl)phenyl]carbamate

(6S,6aS)-6-triphenylsilyloxy-4,5,6,6a-tetrahydro-1H-pentalen-2-one

1-[3-(morpholin-4-yl)propyl]-2,5-dihydro-1H-pyrrole-2,5-dione